Table 2 Summary of 18 studies included in this meta-analysis
Study | Participants | Study design | EIMD protocol | Follow-up time point | Outcomes | |
|---|---|---|---|---|---|---|
Amirsasan et al. [46] | 29 T. M. (23 ± 1) | DB Parallel L (n = 10) H (n = 10) P (n = 9) | Multi-joint and single-joint, Eccentric-dominant exercises (3 sets × 10 reps at 80% 1RM) | Pre, 24, 48 h | CK | NS. |
LDH | NS. | |||||
Areces et al. [68] | 46 T. M + F. (41 ± 7) | DB Parallel B (n = 25) P (n = 21) | Marathon race (45 km) | Pre, ImPost | DOMS | NS. |
Atashak and Baturak [69] | 20 T. M. (22 ± 2) | SB Parallel B (n = 10) P (n = 10) | Eccentric-dominant exercise: 1 sets × 8 reps at 100% 1RM + 1 sets of 100% 1RM until volitional fatigue | Pre, ImPost, 24 h | CK | B < P 24 h |
Barzegari [70] | 40 T. M. (23 ± 4) | SB Parallel B (n = 20) P (n = 20) | Multi-joint and single-joint, Eccentric-dominant exercises: 4 sets × 10 reps at 80% 1RM | Pre, 24, 48 h | CK | NS. |
LDH | NS. | |||||
Dorrell and Gee [47] | 5 T. M. (22 ± 1) | SB Crossover (5 days washout) | 4 multi-joint barbells, Eccentric-dominant exercises: 4 sets × 8 reps at 75% 1RM | Pre, ImPost | DOMS | H + L < P |
Gee and Deniel [63] | 11 T. M. (25 ± 6) | SB Crossover (7 days washout) | 4 multi-joint barbells, Eccentric-dominant exercises: 4 sets × 8 reps at 80% 1RM | Pre, 24 h | DOMS | NS. |
Greer et al. [64] | 9 U. M. (22 ± 3) | SB Crossover (8 days washout) | Cycling: 90 min at 55% VO2max | Pre, ImPost, 24, 48 h | CK | B < P 24, 48 h |
LDH | NS. | |||||
DOMS | B < P 24 h | |||||
Howatson et al. [71] | 12 T. M. (23 ± 2) | DB Parallel B (n = 6) P (n = 6) | Drop jump: 5 sets × 20 reps | Pre, 24, 48, 72, 96 h | CK | B < P 24 h |
DOMS | B < P 24, 48 h | |||||
Jackman et al. [72] | 24 U. M. (NR.) | SB Parallel B (n = 12) P (n = 12) | Unilateral eccentric knee extension: 12 sets × 10 reps at 120% 1RM | Pre, ImPost, 24, 48, 72 h | DOMS | B < P 48, 72 h (flexion) |
Kim et al. [73] | 26 U. M. (22 ± 2) | DB Parallel B (n = 13) P (n = 13) | Cycling: 70% VO2max until exhaustion | Pre, ImPost | CK | NS. |
LDH | NS. | |||||
Koba et al. [60] | 16 T. M. (20 ± 1) | DB Parallel B (n = 8) P (n = 8) | Endurance exercise: 3 times/day (Total 40 km/day) for 5 days | Pre, ImPost | CK | NS. |
LDH | NS. | |||||
DOMS | B < P | |||||
Koo et al. [65] | 5 T. M. (17 ± 1) | SB Crossover (7 days washout) | Rowing race: 2000 m at the maximal intensity | Pre, ImPost, | CK | NS. |
Ra et al. [61] | 10 U. M. (22 ± 1) | DB Parallel B (n = 5) P (n = 5) | Eccentric-dominant exercise: 6 sets × 5 elbow flexions at 90% MVC | Pre, ImPost, 24, 48, 72 h, 96 h | CK | B < P 72, 96 h |
LDH | B < P 72, 96 h | |||||
DOMS | B < P 72, 96 h | |||||
Sheikholeslami-Vatani and Ahmadi [66] | 10 U. F. (22 ± 1.5) | DB Crossover (6 weeks washout) | Eccentric-dominant exercise: 5 sets × 12–15 reps at 50% 1RM | Pre, ImPost, 24 h | CK | NS. |
LDH | NS. | |||||
Shenoy et al. [74] | 20 T. M. (20 ± 1.2) | DB Parallel B (n = 10) P (n = 10) | Drop jump: 5 sets × 20 reps | Pre, 24, 48 h | CK | B < P 24, 48 h |
DOMS | B < P 24, 48 h | |||||
Shimomura et al. [67] | 12 U. F. (22 ± 1.6) | DB Crossover (11 weeks washout) | Eccentric-dominant Squat: 7 Sets × 20 reps with body weight | Pre, ImPost, 24, 48 h | CK | NS. |
DOMS | B < P 24, 48 h | |||||
VanDusseldorp et al. [62] | 20 T. M. (22 ± 1.5) | DB Parallel B (n = 10) P (n = 10) | Eccentric:concentric, Squat: 10 sets × 8 reps at 70% 1RM + Split jump: 5 sets × 20 reps with body weight | Pre, ImPost, 24, 48, 72 h | CK | B < P 48 h |
DOMS | B < P 48, 72 h | |||||
Waldron et al. [75] | 16 T. M + F. (22 ± 1.6; 22 ± 1) | DB Parallel B (n = 8) P (n = 8) | Eccentric-dominant Back squat:10 Sets × 6 reps at 70% 1RM | Pre, ImPost, 24, 48 h | CK | NS. |
DOMS | B < P 24, 48 h | |||||