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Table 4 Responses of β-CTX-1 bone resorption marker to a prolonged, continuous running bout

From: P1NP and β-CTX-1 Responses to a Prolonged, Continuous Running Bout in Young Healthy Adult Males: A Systematic Review with Individual Participant Data Meta-analysis

β-CTX-1 (ng·mL−1)

Mean difference [95% CrI]

SD of difference [95% CrI]

P of increased variation

Proportion of response

Hourly

    

20 min during running

(25 observations / 2 studies)

 − 0.09 [− 0.55 to 0.37]

0.04 [0.03 to 0.05]a

 < 0.001

30–40 during running

(35 observations / 3 studies)

 − 0.06 [− 0.29 to 0.14]

0.10 [0.08 to 0.11]a

0.563

Immediately after

(116 observations / 6 studies)

 − 0.01 [− 0.09 to 0.06]

0.13 [0.12 to 0.14]a

0.996

1 h post-running

(60 observations / 4 studies)

 − 0.02 [− 0.13 to 0.08]

0.10 [0.09 to 0.12]a

0.244

2 h post-running

(60 observations / 4 studies)

 − 0.08 [− 0.18 to 0.01]

0.10 [0.09 to 0.11]a

0.109

3 h post-running

(40 observations / 3 studies)

 − 0.13 [− 0.36 to 0.03]

0.11 [0.10 to 0.13]a

0.576

Daily

    

24 h post-running

(111 observations / 5 studies)

0.01 [− 0.02 to 0.04]

0.12 [0.11 to 0.13]a

 > 0.999

48 h post-running

(81 observations / 4 studies)

0.01 [− 0.06 to 0.07]

0.15 [0.14 to 0.16]a

 > 0.999

72 h post-running

(81 observations / 4 studies)

0.06 [− 0.09 to 0.19]

0.32 [0.29 to 0.35]

 > 0.999

96 h post-running

(30 observations / 2 studies)

 − 0.03 [− 0.27 to 0.24]

0.09 [0.08 to 0.11]

0.311

  1. aEvidence of heteroscedasticity. Proportion of response was only calculated where there was strong evidence of a mean difference