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Table 3 Responses of P1NP bone formation marker to a prolonged, continuous running bout

From: P1NP and β-CTX-1 Responses to a Prolonged, Continuous Running Bout in Young Healthy Adult Males: A Systematic Review with Individual Participant Data Meta-analysis

P1NP (ng·mL−1)

Mean difference [95% CrI]

SD of difference [95% CrI]

P of increased variation

Proportion of response

Hourly

    

20 min during running

(25 observations / 2 studies)

4.2 [0.2 to 8.8]

6.1 [5.2 to 7.3]a

0.088

1.0 75% CrI [0.99 to 1.0]

30–40 during running

(35 observations / 3 studies)

9.2 [5.3 to 14.3]

8.1 [7.1 to 9.4]a

0.700

1.0 75% CrI [0.99 to 1.0]

Immediately after

(75 observations / 5 studies)

12.0 [8.4 to 16.0]

10.2 [9.3 to 11.3]a

 > 0.999

1.0 75% CrI [0.90 to 1.0]

1 h post-running

(75 observations / 5 studies)

1.1 [− 3.1 to 5.2]

5.0 [4.5 to 5.6]a

 < 0.001

2 h post-running

(60 observations / 4 studies)

0.6 [− 3.1 to 4.3]

6.1 [5.5 to 6.8]

0.016

3 h post-running

(40 observations / 3 studies)

0.6 [− 4.6 to 5.7]

4.6 [3.8 to 5.1]a

 < 0.001

Daily

    

24 h post-running

(70 observations / 4 studies)

1.4 [− 0.5 to 3.5]

5.2 [4.8 to 5.8]a

0.172

48 h post-running

(40 observations / 3 studies)

0.6 [− 2.3 to 3.7]

5.9 [5.2 to 7.1]a

0.612

72 h post-running

(40 observations / 3 studies)

0.5 [− 2.8 to 3.9]

7.8 [6.9 to 9.0]

0.999

96 h post-running

(30 observations / 2 studies)

 − 0.4 [− 3.9 to 3.0]

5.4 [4.7 to 6.4]a

0.349

  1. aEvidence of heteroscedasticity. Proportion of response was only calculated where there was strong evidence of a mean difference