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Table 1 List of studies included in the analysis

From: P1NP and β-CTX-1 Responses to a Prolonged, Continuous Running Bout in Young Healthy Adult Males: A Systematic Review with Individual Participant Data Meta-analysis

Study

Running/control data

Bone (re)modelling markers

Assay used

Exercise duration/intensity

Evans et al. [15]

Control

β-CTX-1

P1NP

CLIA (IDS)

CLIA (IDS)

Lehrskov et al. [32]

Running and control

β-CTX-1

P1NP

CLIA (IDS)

CLIA (IDS)

60 min at 75% V̇O2max

Sale et al. [24]

Running

β-CTX-1

P1NP

ECLIA (Roche)

ECLIA (Roche)

120 min at 70% V̇O2max

Scott et al. [16]

Control

β-CTX-1

P1NP

ECLIA (Roche)

RIA (Orion)

-

Scott et al. [33]

Running

β-CTX-1

P1NP

ECLIA (Roche)

RIA (Orion)

60 min at 65% or

75% V̇O2max

Scott et al. [23]

Running and control

β-CTX-1

P1NP

ECLIA (Roche)

RIA (Orion)

60 min at 65% V̇O2max

Townsend et al. [25]

Running

β-CTX-1

P1NP

ECLIA (Roche)

ECLIA (Roche)

75 min at 75% V̇O2max

Varley [29]

Running

β-CTX-1

ELISA (IDS)

120 min at 70% V̇O2max

  1. CLIA chemiluminescence immunoassay; ECLIA electro-chemiluminescence assay; ELISA Enzyme-linked immunosorbent assay; P1NP amino-terminal propeptide of type 1 procollagen; RIA radioimmunoassay; β-CTX-1 carboxy-terminal telopeptide of type 1 collagen