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Table 2 MIT versus HIIT training characteristics

From: Exercise Mode in Heart Failure: A Systematic Review and Meta-Analysis

Study

Groups

Design

Country

Exercise training mode

Exercise intensity

Exercise frequency (days p/w)

Intervention duration (weeks)

Adverse events

Iellamo et al. [28]

MIT

RCT

Italy

Aerobic (uphill treadmill walking)

45–60% HRR (30–45 min)

2–5

12

0

HIIT

RCT

Italy

Aerobic (uphill treadmill walking)

75–80% HRR (4 × 4 min intervals, by 2–4 times)

2–5

12

0

Ellingsen et al. [22]

MIT

RCT

Norway (9 centres)

MIT (treadmill or cycling)

60–70% MHR (47 min)

3

12

NR

HIIT

RCT

Norway (9 centres)

HIIT (treadmill or cycling)

90–95% MHR (4 × 4 min) 38 min session

3

12

NR

Iellamo et al. [29]

MIT

RCT

Italy

Aerobic (uphill treadmill walking)

45–60% HRR (30–45 min)

3

12

0

HIIT

RCT

Italy

Aerobic (uphill treadmill walking)

75–80% HRR (4 × 4 min intervals, by 2–4 times)

3

12

0

Besnier et al. [30]

MIT

RCT

France

MIT (cycling)

60% peak power output (30 min)

5

3.5

0

HIIT

RCT

France

HIIT (cycling)

100% peak power output (Two 8-min blocks of 30 s max output and 30 s active rest)

5

3.5

0

Koufaki et al. [31]

MIT

RCT

UK

MIT (cycling)

40–60% peak VO2 (21–40 min)

3

24

1 (anxiety attack)

HIIT

RCT

UK

HIIT (cycling)

100% peak power output (2 × 15 min bouts of 30 s max output with 1 min active rest between)

3

24

1 (syncope)

Wisløff et al. [32]

MIT

RCT

Norway

moderate continuous—uphill walking

70–75% peak HR

3

12

0

HIIT

RCT

Norway

Aerobic interval training—uphill walking (4 × 4-min intervals)

90–95% peak HR

3

12

0

Dimopoulos et al. [33]

MIT

RCT

Greece

MIT (cycling)

50% WR peak (40 min)

3

12

NR

HIIT

RCT

Greece

HIIT (cycling)

100% WR peak (30 s intervals and 30s rest for 40 min)

3

12

NR

Freyssin et al. [34]

MIT

RCT

France

MIT (cycling and treadmill)

HR corresponding VT1 (45 min)

5

8

0

HIIT

RCT

France

AIT (cycling)

50% steep ramp test (30 s intervals for 40 min)

5

8

0

Fu et al. [35]

MIT

RCT

Taiwan

MIT (cycling)

60% HRR/VO2 peak

3

12

NR

HIIT

RCT

Taiwan

HIIT (cycling)

80% HRR/VO2 peak

3

12

NR

Ulbrich et al. [36]

MIT

RCT

Brazil

MIT (uphill walking)

75% peak HR

3

12

0

HIIT

RCT

Brazil

HIIT (uphill walking)

95% peak HR (3 min intervals with 3 min active recovery, 4–6 times)

3

12

0

Donelli da Silveira et al. [37]

MIT

RCT

Brazil

MIT (treadmill)

50–60% peak VO2

3

12

0

HIIT

RCT

Brazil

HIIT (treadmill)

80–90% peak VO2

3

12

0

Angadi et al. [38]

MIT

RCT

USA

MIT (treadmill)

60–70% peak HR

3

4

0

HIIT

RCT

USA

HIIT (treadmill)

80–85% peak HR

3

4

0

Mueller et al. [23]

MIT

RCT

Germany

HIIT (cycling)

80–90% HRR

5

12

NR

HIIT

RCT

Germany

Aerobic (cycling)

35–50% HRR

3

12

NR

  1. HIIT, High-intensity interval training; MIT, moderate intensity training; RCT, randomised controlled trial; MHR, maximal heart rate; HRR, heart rate reserve; WR, work rate; VO2, volume oxygen