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Table 2 Baseline and change scores for fasting and IVGTT parameters in STRRIDE I by group

From: Differential Effects of Amount, Intensity, and Mode of Exercise Training on Insulin Sensitivity and Glucose Homeostasis: A Narrative Review

 

Control

(n = 58)

Low amount/moderate intensity

(n = 57)

Low amount/vigorous intensity

(n = 58)

High amount/vigorous intensity

(n = 64)

Baseline

Change

p

Baseline

Change

p

Baseline

Change

p

Baseline

Change

p

Fasting parameters

Glucose (mmol/L)

5.0 (0.6)

0.2 (0.5)

**

5.1 (0.5)

− 0.01 (0.5)

NS

5.1 (0.5)

0.1 (0.5)

NS

5.2 (0.6)

0.03 (0.5)

NS

Insulin (pmol/L)

51.0 (28.2)

5.4 (19.8)

*

61.8 (48.6)

− 15.0 (33.6)

**

52.8 (24.6)

− 9.0 (24.6)

**

57.6 (19.8)

− 7.8 (19.8)

**

HOMA-IR

1.1 (0.6)

0.1 (0.4)

*

1.3 (1.0)

− 0.3 (0.7)

**

1.2 (0.7)

− 0.2 (0.5)

**

1.2 (0.7)

− 0.2 (0.4)

**

LP-IRa

53.1 (25.2)

− 0.3 (17.4)

NS

60.0 (25.0)

− 9.3 (15.5)

***

52.1 (25.4)

− 5.2 (15.9)

*

54.7 (24.3)

− 6.1 (13.8)

**

DRIa

39.9 (21.3)

− 0.2 (12.0)

NS

43.7 (18.3)

− 4.7 (14.4)

*

43.0 (20.0)

− 2.6 (8.9)

NS

44.2 (20.4)

− 1.5 (12.2)

NS

IVGTT parameters

DI

1562 (1444)

− 65 (893)

NS

1270 (1147)

742 (1680)

**

1533 (1362)

255 (1023)

NS

1305 (1121)

255 (685)

**

AIRg (mU/L/min)

490.6 (431.2)

22.1 (232.6)

NS

457.3 (334.1)

− 9.8 (207.3)

NS

445.5 (352.7)

− 42.8 (216.4)

NS

505.6 (426.6)

− 76.6 (217.6)

**

Si (mU/L/min)

3.5 (2.1)

− 0.4 (1.7)

NS

3.1 (2.2)

1.7 (2.5)

***

3.7 (2.1)

0.8 (1.8)

**

3.2 (2.5)

1.2 (2.1)

***

  1. Data presented as means (SD)
  2. AIRg, acute insulin response to intravenous glucose; DI, disposition index; DRI, Diabetes Risk Index; HOMA, homeostatic model assessment [(fasting glucose × fasting insulin)/22.5]; IVGTT, intravenous glucose tolerance test; LP-IR, Lipoprotein Insulin Resistance Index; NS, not significant; Si, insulin sensitivity index
  3. *p < 0.05; **p < 0.01; ***p < 0.001
  4. aLP-IR and DRI sample sizes are: Con (n = 53); Low/Mod (n = 44); Low/Vig (n = 48); High/Vig (n = 49)