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Table 2 Mean (± SD) pharmacokinetic response variables for bicarbonate in the SOL and CAP conditions, together with the statistical significance of the difference

From: A Novel Ingestion Strategy for Sodium Bicarbonate Supplementation in a Delayed-Release Form: a Randomised Crossover Study in Trained Males

Outcome SOL CAP t test P value
Tlag (min) 20.0 ± 0.0* 31.7 ± 10.3* − 3.92 0.002
Tmax (min) 71.7 ± 18.0** 120.0 ± 28.9** − 5.35 < 0.0005
Cmax (mmol L−1) 31.2 ± 1.1 31.8 ± 1.3 − 1.66 0.125
Cmax (mmol L−1) 6.4 ± 1.3 6.5 ± 1.1 − 0.46 0.658
AUC0-3h (mmol min L−1) 5277.9 ± 173.9 5286.0 ± 197.9 − 0.13 0.899
  1. The asterisk denotes significant difference between SOL and CAP (*P < 0.05, **P < 0.0005). Tlag time to commence change in bicarbonate concentration, Tmax time to peak concentration, Cmax peak bicarbonate concentration, ∆Cmax absolute change in bicarbonate concentration, AUC0-3h area under the concentration-time curve