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Table 2 Mean (± SD) pharmacokinetic response variables for bicarbonate in the SOL and CAP conditions, together with the statistical significance of the difference

From: A Novel Ingestion Strategy for Sodium Bicarbonate Supplementation in a Delayed-Release Form: a Randomised Crossover Study in Trained Males

Outcome

SOL

CAP

t test

P value

Tlag (min)

20.0 ± 0.0*

31.7 ± 10.3*

− 3.92

0.002

Tmax (min)

71.7 ± 18.0**

120.0 ± 28.9**

− 5.35

< 0.0005

Cmax (mmol L−1)

31.2 ± 1.1

31.8 ± 1.3

− 1.66

0.125

∆Cmax (mmol L−1)

6.4 ± 1.3

6.5 ± 1.1

− 0.46

0.658

AUC0-3h (mmol min L−1)

5277.9 ± 173.9

5286.0 ± 197.9

− 0.13

0.899

  1. The asterisk denotes significant difference between SOL and CAP (*P < 0.05, **P < 0.0005). Tlag time to commence change in bicarbonate concentration, Tmax time to peak concentration, Cmax peak bicarbonate concentration, ∆Cmax absolute change in bicarbonate concentration, AUC0-3h area under the concentration-time curve
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