Table 6 Proposed cutoffs for overtraining syndrome
Suggested cutoffs | Practical application | |
|---|---|---|
Salivary cortisol (ng/dL) 30 min after awakening | > 530 ng/dL | Highly predictable of exclusion of OTS (93.9%). |
370 ng/dL | Highly accurate (80%), but unable to help diagnosis OTS | |
Serum cortisol (μg/dL) 30 min after hypoglycemia in ITT | > 20.5 μg/dL | High negative predictive value for OTS (100%) |
> 17.0 μg/dL | High positive predictive value for OTS, although not specific (28.6%) | |
19.1 μg/dL | High accuracy (84.6%), but not precise for confirmation or exclusion of OTS | |
Cortisol increase during ITT (μg/dL) | > 9.5 μg/dL | 100% specific to exclude OTS |
Plasma ACTH (pg/mL) 30 min after hypoglycemia in ITT | > 106 pg/mL | High negative predictive value (92.9%) and highly accurate (80%) |
ACTH increase during ITT (pg/mL) | < 35 pg/mL | 80% accurate to distinguish OTS from ATL |