Table 5 Modulation of TLR2 and TLR4 after acute resistance exercise
Authors | Sample | Disease | Intensity and duration | Post-exercise results | ||
|---|---|---|---|---|---|---|
TLR | Cytokine | Other | ||||
Millard et al. 2013 [123] | Adults | No disease | 120–150 beats/min, 68.8 s (up and down 150 steps) | ↔TLR2 | ↔IFN-γ | ↑CD3−/CD56+NK, ↓NK CD56bright Short exercise did not affect NK cytotoxicity. |
Fernandez-Gonzalo et al. 2012 [88] | Adults | No disease | 40–50 MVIC, 18 acute eccentric bouts | ↓TLR4 | ↓TNF-α | ↓CD14, ↓MyD88, ↓TRIF, ↓TRAF6, ↓p65, ↓phospho-IκB, ↓phospho-ERK1/2, ↓CRP, 2 h after the 2nd acute session. |
Fernandez-Gonzalo et al. 2014 [122] | Adults | No disease | 40–50 MVIC, 18 acute eccentric bouts | ↓TLR4 | ↓TNF-α | ↓CD14, ↓MyD88, ↓TRIF, ↓TRAF6, ↓p65, ↓phospho-IκB, ↓phospho-ERK1/2, ↓CRP, 2 h after the 2nd acute session. |
McFarlin et al. 2004 [29] | Elderly | No disease | 80% 1 RM, 1 bout/3 sets/10 repetitions | ↓TLR4 | ↔TNF-α ↔IL-6 ↔IL-1β | ↔CD14 |