Sports Medicine - Open

Table 9 Comparison of genotypic and allelic frequency distribution between participants of the Indian Army and general Indian population

From: Polygenic study of endurance-associated genetic markers ACE I/D, ACTN3 Arg(R)577Ter(X), CKMM A/G NcoI and eNOS Glu(G)298Asp(T) in male Gorkha soldiers

			Indo-Aryan			Dravidian			General Population
			Indian Army	General population		Indian Army	General population		Indian Army	General population
SNP	Variants	Genotype			p ^*			p ^*			p ^*
rs1799752	ACE I/D	II	0.25^a	0.26^b	0.71	0.29^a	0.37^e	0.18
		ID	0.50^a	0.54^b		0.53^a	0.42^e
		DD	0.24^a	0.20^b		0.18^a	0.21^e
		Allele
		I	0.51^a	0.53^b	0.55	0.56^a	0.58^e	0.64
		D	0.49^a	0.46^b		0.44^a	0.42^e
rs1815739	ACTN3 Arg(R) 577Ter(X)	RR	0.18^a	0.16^c	0.04	0.24^a
		RX	0.56^a	0.45^c		0.48^a	NA	NA
		XX	0.26^a	0.39^c		0.28^a
		Allele
		R	0.46^a	0.39^c	0.05	0.48^a
		X	0.54^a	0.61^c		0.52^a
rs1799983	eNOS Glu298Asp	GG	0.64ⁱ	0.71^d	0.12	0.73ⁱ	0.74^f	0.45
		GT	0.33ⁱ	0.27^d		0.25ⁱ	0.26^f
		TT	0.01ⁱ	0.07^d		0.01ⁱ	0.00^f
		Allele
		G	0.81ⁱ	0.85^d	0.90	0.86ⁱ	0.87^f	0.76
		T	0.18ⁱ	0.15^d		0.14ⁱ	0.13^f
rs1042713	ADRB2 Arg16Gly	GG							0.31^g	0.25^k	0.49
		AG							0.53^g	0.53^k
		AA							0.16^g	0.22^k
		Allele
		G							0.56^g	0.52^k	0.25
		A							0.43^g	0.48^k
rs41317140	REN C/T	CC	0.62^j	0.69^h	0.35
		CT	0.35^j	0.31^h
		TT	0.02^j	0.00^h
		Allele
		C	0.80^j	0.84^h	0.29
		T	0.20^j	0.16^h

Data for CKMM is not available in Indian general population
NA data not available
*Significance for genotypic and allelic frequency is assumed when p < 0.05. The significant p values are italicized
^a[10]; ^b[76]; ^c[77]; ^d[78]; ^e[79]; ^f[80]; ^g[23]; ^h[81]; ⁱPresent study; ^junpublished; ^kvalues computed by clubbing the data from [82] and [83]

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