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Table 1 Heart rate, venous bicarbonate and pH for placebo, 2 and 4 mg nicotine gum. Values are mean ± SD, n = 9

From: A Randomised, Placebo-Controlled, Crossover Study Investigating the Effects of Nicotine Gum on Strength, Power and Anaerobic Performance in Nicotine-Naïve, Active Males

  Pre Post
PLA NIC-2 NIC-4 PLA NIC-2 NIC-4
HR
(beats min−1)
65 ± 11 67 ± 9 64 ± 9 117 ± 15a 125 ± 19a,b 123 ± 15a,b
HCO3
(mmol L−1)
25 ± 5 27 ± 2 25 ± 5 14 ± 4a 15 ± 3a 16 ± 4a
pH 7.46 ± 0.08 7.52 ± 0.06b,c 7.47 ± 0.06 7.29 ± 0.10a 7.35 ± 0.08a 7.30 ± 0.10a
  1. Heart rate (HR) at rest pre-treatment (Pre) and during cycling at 100 W post-treatment (Post); bicarbonate (HCO3 ) and pH before (Pre) and after (Post) WAnT; placebo (PLA), 2 mg (NIC-2) and 4 mg (NIC-4) trials
  2. aSignificant difference to corresponding Pre value
  3. bSignificant difference to corresponding PLA value
  4. cSignificant difference to corresponding NIC-4 value