Skip to main content

Advertisement

Table 1 Patient demographics and outcomes treated by image-guided hyaluronic acid injection

From: Image-Guided Hyaluronic Acid Injection and Knee Bracing Significantly Improve Clinical Outcomes for High-Grade Osteoarthritis

  OA grade 2 (n = 58) OA grade 3 (n = 98) OA grade 4 (n = 51) P value X 2 or ANOVA
Age (mean, SD) 56.3 ± 12.4 64.0 ± 11.3 69.8 ± 12.2 P < 0.0001
Male gender (n, [%]) 20 (35 %) 41 (42 %) 21 (42 %) P = 0.62
Body mass index (mean, SD) 29.6 ± 6.5 31.2 ± 6.5 34.6 ± 9.3 P < 0.01
Never smoked (n, [%]) 49 (85 %) 86 (88 %) 42 (82 %) P = 0.29
Physical therapy (n, [%]) 27 (47 %) 44 (45 %) 20 (39 %) P = 0.72
Daily analgesics (n, [%]) 23 (40 %) 41 (42 %) 26 (51 %) P = 0.39
Knee bracing (n, [%]) 20 (35 %) 60 (61 %) 31 (61 %) P < 0.01
Fish oil (n, [%]) 43 (74 %) 64 (65 %) 43 (84 %) P = 0.05
Function index baseline (mean, SD) 34.7 ± 16.1 46.0 ± 15.4 48.1 ± 13.3 P < 0.0001
Index at 6 months (mean, SD) 27.2 ± 15.9 26.3 ± 14.9 36.4 ± 17.7 P < 0.01
Mean improvement (±SD) 6.7 ± 19.0 19.3 ± 16.8 12.5 ± 14.6 P < 0.001
Percentage improvement (±SD) 19 % ± 32 % 40 % ± 32 % 26 % ± 31 % P < 0.001
>9-point improvement (n, [%]) 32 (55 %) 67 (68 %) 26 (51 %) P = 0.07
Average pain baseline (mean, SD) 5.5 ± 2.5 6.2 ± 2.1 7.1 ± 2.1 P < 0.01
Pain at 6 months (mean, SD) 3.9 ± 2.0 3.8 ± 2.1 5.2 ± 2.5 P < 0.01
Mean improvement (mean, SD) 1.66 ± 2.1 2.74 ± 2.5 2.3 ± 2.8 P = 0.05
Percentage improvement (±SD) 21 % ± 38 % 40 % ± 37 % 25 % ± 47 % P = 0.04
  1. Univariate analysis of patient demographics and treatment outcomes relative to knee osteoarthritis (OA) severity (grades 2–4). Data are presented as the mean ± standard deviation (SD) or percent (%) within OA grade