Skip to main content

Table 1 Studies investigating changes in body composition markers following exercise training in hypoxia compared to normoxia in middle-aged and older adults

From: Effect of Hypoxia Conditioning on Body Composition in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis

Study

Participant Characteristics

Intervention

Participants (M/F)

Age

BMI

Duration

Frequency

Type

Exercise intensity

Hypoxia severity/duration per session

Type of hypoxia

Outcome

HYP

NOR

HYP

NOR

Abdallah et al. [52]

16 (10/6)

15 (13/2)

51.0 ± 8.3

52.0 ± 7.5

H:31.5 ± 4.0 N:32.4 ± 4.8

8wks

3days/wk

High-intensity interval training

80% Wpeak (HYP)/ 100% Wpeak (NOR)

FiO2 =  ~ 12%/35-48min

Normobaric

BMI, LM, FM

Allsopp et al. [42]

10 (6/4)

10 (6/4)

65.9 ± 1.1

64.0 ± 0.8

H: 24.9 ± 1.1 N: 23.9 ± 0.8

8wks

2days/wk

Resistance

70% 1RM

FiO2 = 14.4%/60min

Normobaric

BMI, LM, FM (total, leg, arm, trunk)

Camacho et al. [49]

10 (3/7)

11 (6/5)

73.5 ± 4.7

70.2 ± 6.4

H: 28.9 ± 4.2 N: 29.5 ± 4.8

18wks

2days/wk

Whole-body vibration

2.54 G12.6 Hz/4 mm

FiO2 = 16.2%/16min

Normobaric

LM% (total, trunk, right leg)

Camacho et al. [50]

9 (2/7)

10 (5/5)

72.6 ± 3.6

68.8 ± 5.3

H: 28.3 ± 4.4 N: 27.8 ± 5.8

18wks

2days/wk

Whole-body vibration

12.6 Hz/4 mm

FiO2 = 16.2%/21min

Normobaric

LM

Chacaroun et al. [43]

12 (11/1)

11 (8/3)

52.0 ± 12.0

56.0 ± 11.0

H: 31.2 ± 2.4 N: 31.8 ± 3.2

8wks

3days/wk

Aerobic

75% HRmax

FiO2 =  ~ 13.0%/45min

Normobaric

BMI, LM/ LM%, FM/ FM%

Hanneset al. [53]

16 (4/12)

16 (6/10)

50.3 ± 10.3

52.4 ± 7.9

H: 37.9 ± 8.1 N: 36.3 ± 4.0

8months

2days/wk

Aerobic

65–70% HRmax

FiO2 =  ~ 14.0%/180min

Normobaric

BMI, MM%, FM%

Nishiwaki et al. [48]

7 (0/7)

7 (0/7)

56.0 ± 1.0

56.0 ± 1.0

 > 24.0

8wks

4days/wk

Aerobic

50% V̇O2peak

Simulation of 2000 m (~ 600 mmHg)/ 120min

Hypobaric

BMI, LM, BF (subcutaneous, preperitoneal, total%)

Park et al. [51]

12 (12/0)

12 (12/0)

66.5 ± 0.9

66.5 ± 0.7

H: 26.0 ± 0.6 N: 25.6 ± 0.4

12wks

3days/wk

Aerobic + Resistance

60%-70% HRmax/60%-70% 1RM

FiO2 = 15.0%/90-120min

Normobaric

LM, BF%

Pramsohler et al. [41]

19 (7/12)

16 (5/11)

80.2 ± 7.2

82.0 ± 7.8

H: 25.2 ± 5.3 N: 25.8 ± 5.7

3wks

7days/3wks

Aerobic

80% eV̇O2peak

FiO2 = 15.3%/30min

Normobaric

BMI

Timon et al. [40]

17 (NR)

18 (NR)

68.5 ± 3.8

70.4 ± 3.3

H: 26.4 ± 3.3 N: 27.1 ± 3.9

24wks

3days/wk

Resistance

RPE 6–8

FiO2 = 16.1%/45min

Normobaric

LM, FM

Törpel et al. [35]

19 (9/10)

17 (9/8)

68.1 ± 4.6

67.8 ± 4.1

H: 27.6 ± 4.2 N: 26.9 ± 3.6

5wks

4days/wk

Resistance

40% 1RM

SpO2 =  ~ 80–85%/180min

Normobaric

LM, FM

Wiesner et al. [37]

24 (10/14)

21 (8/13)

42.2 ± 1.2

42.1 ± 1.7

H: 33.1 ± 0.3 N: 32.5 ± 0.8

4wks

3days/wk

Aerobic

65% V̇O2max

FiO2 = 15%/60min

Normobaric

BMI, LM%, FM%

  1. M male, F female, NR not reported, HYP hypoxia, NOR normoxia BMI body mass index, wks weeks, RM repetition maximum, RPE rating of perceived exertion, mins minutes, FiO2 fraction of inspired oxygen, SpO2 arterial oxygen saturation, Wpeak maximal workload, V̇O2peak peak oxygen uptake, V̇O2max maximal oxygen uptake, HRmax maximal heart rate, LM lean mass, FM fat mass, FM% fat mass percentage, LM% lean mass percentage, MM% muscle mass percentage, BF body fat