Table 3 Moderator subgroup analysis for VO_2peak

VO_2peak overall

SMD = 0.18

CI: − 0.09, 0.44

p = 0.19

Sex

Male:

SMD = 0.28

CI: − 0.21, 0.76

p = 0.27

Mixed:

SMD = 0.10

CI: − 0.24, 0.44

p = 0.55

Health Status

Healthy:

SMD = 0.21

CI: − 0.11, 0.52

p = 0.20

Clinical:

SMD = 0.11

CI: − 0.37, 0.58

p = 0.66

Oxygen

Normoxia:

SMD = 0.07

CI: − 0.23, 0.37

p = 0.65

Hypoxia:

SMD = 0.48

CI: − 0.22, 1.19

p = 0.18

Route of Administration

BRJ:

SMD = 0.25

CI: − 0.05, 0.55

p = 0.10

Other:

SMD = − 0.06

CI: − 0.59, 0.47

p = 0.83

Acute Dosing Prior

Yes

SMD = 0.23

CI: − 0.09, 0.55

p = 0.17

No

SMD = 0.06

CI: − 0.39, 0.52

p = 0.78