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Fig. 3 | Sports Medicine - Open

Fig. 3

From: Acute Effects of Single Versus Combined Inhaled β2-Agonists Salbutamol and Formoterol on Time Trial Performance, Lung Function, Metabolic and Endocrine Variables

Fig. 3

Concentrations of β2-agonists determined in serum for salbutamol, formoterol and the combined dosage salbutamol + formoterol in the whole group as well as separated in male and female participants. A Acute serum salbutamol inhalation resulted in a concentration increase that gradually decreased at 3 h post-TT and 24 h post-TT. The absolute concentration was higher in females compared to males. B Administration of formoterol showed the highest concentration post-TT in all participants and was decreased at 3 h with higher values observed in females. C The combined medication resulted in higher salbutamol concentrations for males compared to female participants post-TT, whereas at 3 h and 24 h post-TT females still had higher detectable salbutamol serum concentrations. D Formoterol concentrations in females were significantly higher after salbutamol + formoterol inhalation at post-TT and 3 h post-TT compared to their male counterparts. All data are presented as mean ± standard deviation. Significance set at *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001

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