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Table 2 Z-score equations of CPET parameters

From: Reference Values of Cardiopulmonary Exercise Test Parameters in the Contemporary Paediatric Population

CPET parameters

Sex

Z-score equations

N

R2

5th percentile

Median

95th percentile

HRmax (bpm)

All gender

\({\text{Z - score}} = \frac{{\left( {{\text{HR}}_{{{\text{max}}}} \left( {{\text{bpm}}} \right) - 188.1} \right)}}{8.9}\)

909

–

− 1.70

− 0.01

1.67

RERmax

Girls

\({\text{Z - score}} = \frac{{{\text{RER}} - 0.985 - 0.015 \times {\text{age}}_{{\left( {{\text{years}}} \right)}} }}{0.098}\)

431

0.14

− 1.46

0.01

1.73

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{RER}}}} + 2.01 - 0.475 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} + 0.064 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.0769}\)

477

0.16

− 1.79

0.08

1.44

Workloadmax (Watts)

Girls

\({\text{Z - score}} = \frac{{\ln_{{{\text{load}}}} + 5.951 - 1.947 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.39 \times \ln_{{{\text{age}}\left( {{\text{years}}} \right)}} }}{0.1932}\)

390

0.60

− 1.61

− 0.02

1.58

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{load}}}} + 7.662 - 2.309 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.408 \times \ln_{{{\text{age}}\left( {{\text{years}}} \right)}} }}{0.1713}\)

419

0.76

− 1.82

0.09

1.66

O2 pulsemax (mL)

Girls

\({\text{Z - score}} = \frac{{\ln_{{02{\text{pulse}}}} + 6.266 - 1.049 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} + 0.091 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} - 1.147 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} }}{0.1484}\)

432

0.69

− 1.66

− 0.04

1.82

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{02{\text{pulse}}}} + 8.04 - 0.15 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} - 1.946 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} }}{0.1458}\)

477

0.77

− 1.64

− 0.01

1.60

VAT (mL/min)

Girls

\({\text{Z - score}} = \frac{{\ln_{{{\text{VAT}}\left( {\text{mL/min}} \right)}} - 1.603 - 0.7875 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.3824 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.1872}\)

432

0.54

− 1.55

− 0.02

1.73

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{VAT}}\left( {\text{mL/min}} \right)}} + 1.5616 - 1.5681 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.228 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.1714}\)

477

0.68

− 1.83

− 0.08

1.65

VE/VCO2 slope

Girls

\({\text{Z - score}} = \frac{{\ln_{{\frac{{{\text{VE}}}}{{{\text{VCO}}_{2} }}{\text{slope}}}} - 3.80 + 0.158 \times \ln_{{{\text{age}}\left( {{\text{years}}} \right)}} }}{0.1411}\)

423

0.06

− 1.61

0.03

1.74

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{\frac{{{\text{VE}}}}{{{\text{VCO}}_{2} }}{\text{slope}}}} - 4.016 + 0.255 \times \ln_{{{\text{age}}\left( {{\text{years}}} \right)}} }}{0.123}\)

469

0.19

− 1.67

− 0.03

1.62

OUES

Girls

\({\text{Z - score}} = \frac{{\ln_{{{\text{OUES}}}} - 0.4262 - 1.1554 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.3173 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.1906}\)

301

0.57

− 1.67

− 0.03

1.61

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{OUES}}}} + 3.1486 - 2.0259 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.1520 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.1848}\)

355

0.67

− 1.71

− 0.02

1.62

VTmax (L)

Girls

\({\text{Z - score}} = \frac{{\ln_{{{\text{VTmax}}\left( {\text{L}} \right)}} + 12.1409 - 2.3285 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.17293 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.17085}\)

432

0.72

− 1.51

− 0.04

1.64

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{VTmax}}\left( {\text{L}} \right)}} + 13.4373 - 2.6582 \times \ln_{{{\text{height}}\left( {{\text{cm}}} \right)}} - 0.0998 \times \ln_{{{\text{weight}}\left( {{\text{Kg}}} \right)}} }}{0.1727}\)

477

0.78

− 1.68

0.00

1.61

RRmax (1/min)

Girls

\({\text{Z - score}} = \frac{{{\text{RR}}\left( {1/\min } \right) - 73.62 + 0.161 \times {\text{height}}\left( {{\text{cm}}} \right)}}{9.56}\)

428

0.05

− 1.54

− 0.05

1.58

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{RR\left( {1/\min } \right)}} - 4.42 + 0.133 \times \ln_{{{\text{weight}}\left( {{\text{kg}}} \right)}} }}{0.194}\)

467

0.07

− 1.72

0.04

1.47

BR (%)

Girls

\({\text{Z - score}} = \frac{{{\text{BR}}\left( \% \right) - 28.70}}{15.48}\)

432

–

− 1.85

0.07

1.56

 

Boys

\({\text{Z - score}} = \frac{{{\text{BR}}\left( \% \right) - 24.31}}{13.71}\)

476

–

− 1.77

0.05

1.51

VEqCO2max

All gender

\({\text{Z - score}} = \frac{{\ln_{{{\text{VeqCO}}_{2} }} - 3.421}}{0.1195}\)

909

–

− 1.66

0

1.66

VEqO2max

Girls

\({\text{Z - score}} = \frac{{\ln_{{{\text{VeqO}}_{2} }} - 3.575}}{0.1602}\)

432

–

− 1.56

0.01

1.60

 

Boys

\({\text{Z - score}} = \frac{{\ln_{{{\text{VeqO}}_{2} }} - 3.544}}{0.1488}\)

477

–

− 1.62

− 0.06

1.80

  1. BR breathing reserve; HRmax maximum heart rate; O2 pulsemax maximum oxygen pulse; OUES oxygen uptake efficiency slope; RERmax maximum respiratory exchange ratio; RRmax maximum respiratory rate; SD standard deviation; VAT ventilatory anaerobic threshold; VEqCO2max maximum ventilatory equivalent for CO2; VEqO2max maximum ventilatory equivalent for O2; VTmax maximum tidal volume