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Table 1 Overview of the intervention studies assessing drop sets and the effect upon muscle hypertrophy

From: Effects of Drop Sets on Skeletal Muscle Hypertrophy: A Systematic Review and Meta-analysis

Reference

Sample (N)

Sex

Training status

Duration (weeks)

Exercise prescription

Training frequency

Condition

Hypertrophy measurement

Main findings

Ozaki et al. [17]

9 (within-subject design)

Men

Untrained

8

Dumbbell curls

2–3 times a week

HL: s, 3; I, 80%; r, to CF; p, 3 min

LL: s, 3; I, 30%; r, to CF; p, 90 s

DS: s, 1; I, 80–65–50–40–30%; r, to CF

MRI

Both groups significantly increased CSA, but there was no time × group effect

Fink et al. [16]

16

Men

Active

6

Triceps push-down

Twice a week

Trad: s, 3; r, 12 to CF; I, 12 RM; p, 90 s

DS: s, 1; r, 12; I, 12 RM to CF, 3 drops at 20% each

MRI

Both groups significantly increased CSA, but there was no time × group effect

Fisher et al. [29]

41

Both

Resistance trained

12

Chest press, leg press, pull-down

Twice a week

Trad: s, 1; r, 8–12 to CF DS: s, 1; r, 8–12 to CF, 1 drop at 30%

HLDS: s, 1; r, 4 to CF, 2 drops at 20% each

Bod Pod

No significant changes in body composition were found in either of the groups

Angleri et al. [14]

32 (within-subject design)

Men

Resistance trained

12

Leg press, leg extension

Twice a week

Trad: s, 3–5; r, 6–12 to CF; I, 75%; p, 2 min

CP: s, 3–5; r, 6–15 to CF; I, 65–85%; p, 2 min

DS: s, 3–5; r, to CF; I, 50–75%, 1–2 drops at 20%; p, 2 min

Ultrasound

Both groups significantly increased CSA, but there was no time × group effect

Varović et al. [18]

16

(within-subject design)

Men

Recreationally active

8

Unilateral leg extension

1–3 times a week

Trad: r, to CF; I, 15 RM; p, 120 s

DS: r, to CF; I, 5 RM, 1 drop at 20%, 1 drop at 10–15%

Ultrasound

Both Trad and DS significantly increased muscle thickness in VL and RF. In RF at 30% and 50% muscle length, there was also a time × group effect favoring DS

Enes et al. [15]

28

Men

Resistance trained

8

Back squat, leg press, leg extension

Twice a week

DS: s, 3; r, 10 + 6; I, 75 + 55%; r, 120 intersets

RP: s, 3; r, 10 + 6; I, 75%; p, 20 s intrasets, 120 s interset Trad: s, 4; r, 12; I, 70%; p, 120 s interset

Ultrasound

Both Trad and DS significantly increased muscle thickness in the proximal and middle VL, but not in the distal part. There was no time × group effect

  1. DS drop set; Trad traditional set; HL high load; LL low load; RP rest pause; CP crescent pyramid; CSA cross-sectional area; s set; r repetition; p pause; I intensity (percentage of 1 repetition maximum); CF concentric failure; RM repetition maximum; intraset between repetitions; interest between sets; MRI magnetic resonance imaging; VL vastus lateralis; and RF rectus femoris