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Table 3 Diagnostic performance of the LEAF-Q subcategories (injury, gastrointestinal symptoms, and menstrual function) to identify individuals with the associated indicators of the Triad, based on the original publication

From: Evaluating the Suitability of the Low Energy Availability in Females Questionnaire (LEAF-Q) for Female Football Players

Cut off-score

AUC [95% CI]

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Injury ≥ 2

     

 BMD (Z score < -1)

     

  Lumbar spine

0.78 [0.61, 0.96]

100

32

2

100

  Lumbar spinea

 

100

66

5

100

  Hip

 

  History of Stress fracture

0.43 [0.25, 0.62]

54

28

18

68

 BMD (Z score < 0)

     

  Lumbar spine

0.77 [0.59, 0.95]

80

33

10

95

  Lumbar spinea

 

80

69

19

97

  Hip

0.47 [0.01, 0.92]

50

31

2

95

  Hipa

 

50

66

5

97

Gastrointestinal symptoms ≥ 2

     

 RMR < 30 kcal/kg/FFMb

0.45 [0.31, 0.60]

56

46

42

59

Menstrual function ≥ 4

     

 Amenorrhea (27)b

0.93 [0.83, 1.03]

88

90

78

94

  1. LEA Low energy availability
  2. a = best performing cut-off score based on Youden’s index; b = indicates that the original cut-off score is the best performing based on Youden’s index