SNP | Variants | Overall | (1) Gurung | (2) Magar | (3) Rai | (4) Tamang | (5) Limbu | Comparison of groups | Genotypica frequency | Alleleb frequency | |
---|---|---|---|---|---|---|---|---|---|---|---|
Frequency | Level of significance (p) | ||||||||||
rs1799752 | ACE I/D | Genotype | |||||||||
II | 0.427 | 0.465 | 0.349 | 0.466 | 0.509 | 0.430 | 1 vs 2 | 0.14 | 0.04 | ||
ID | 0.467 | 0.438 | 0.471 | 0.466 | 0.452 | 0.507 | 1 vs 3 | 0.81 | 0.37 | ||
DD | 0.104 | 0.095 | 0.178 | 0.066 | 0.037 | 0.061 | 1 vs 4 | 0.45 | 0.38 | ||
Allele | 1 vs 5 | 0.62 | 0.99 | ||||||||
I | 0.671 | 0.684 | 0.585 | 0.700 | 0.735 | 0.684 | 2 vs 3 | 0.08 | 0.03 | ||
D | 0.338 | 0.315 | 0.414 | 0.300 | 0.264 | 0.315 | 4 vs 2 | 0.02 | 0.007 | ||
2 vs 5 | 0.07 | 0.05 | |||||||||
HWE p | 0.381 | 0.893 | 0.751 | 0.389 | 0.230 | 0.156 | 3 vs 4 | 0.75 | 0.55 | ||
3 vs 5 | 0.90 | 0.79 | |||||||||
4 vs 5 | 0.63 | 0.38 | |||||||||
rs1815739 C/T | ACTN3 Arg(R)577Ter(X) | Genotype | |||||||||
RR | 0.366 | 0.397 | 0.308 | 0.366 | 0.396 | 0.413 | 1 vs 2 | 0.33 | 0.13 | ||
RX | 0.478 | 0.465 | 0.487 | 0.466 | 0.471 | 0.492 | 1 vs 3 | 0.87 | 0.61 | ||
XX | 0.155 | 0.139 | 0.203 | 0.166 | 0.132 | 0.092 | 1 vs 4 | 0.99 | 0.97 | ||
Allele | 1 vs 5 | 0.71 | 0.58 | ||||||||
R | 0.605 | 0.630 | 0.552 | 0.600 | 0.632 | 0.661 | 2 vs 3 | 0.69 | 0.39 | ||
X | 0.394 | 0.369 | 0.447 | 0.400 | 0.367 | 0.338 | 4 vs 2 | 0.38 | 0.16 | ||
2 vs 5 | 0.10 | 0.04 | |||||||||
HWE p | 0.970 | 0.99 | 0.882 | 0.829 | 0.917 | 0.423 | 3 vs 4 | 0.86 | 0.62 | ||
3 vs 5 | 0.45 | 0.31 | |||||||||
4 vs 5 | 0.79 | 0.63 | |||||||||
rs8111989 T/C | CKMM A/G NcoI | Genotype | |||||||||
AA | 0.655 | 0.630 | 0.634 | 0.833 | 0.603 | 0.600 | 1 vs 2 | 0.89 | 0.86 | ||
AG | 0.296 | 0.287 | 0.300 | 0.150 | 0.377 | 0.369 | 1 vs 3 | 0.02 | 0.003 | ||
GG | 0.048 | 0.082 | 0.065 | 0.016 | 0.018 | 0.030 | 1 vs 4 | 0.22 | 0.72 | ||
Allele | 1 vs 5 | 0.31 | 0.83 | ||||||||
A | 0.803 | 0.773 | 0.784 | 0.908 | 0.792 | 0.784 | 2 vs 3 | 0.02 | 0.003 | ||
G | 0.196 | 0.226 | 0.215 | 0.091 | 0.207 | 0.215 | 4 vs 2 | 0.32 | 0.86 | ||
2 vs 5 | 0.44 | 0.99 | |||||||||
HWE p | 0.244 | 0.280 | 0.221 | 0.442 | 0.283 | 0.456 | 3 vs 4 | 0.02 | 0.01 | ||
3 vs 5 | 0.01 | 0.007 | |||||||||
4 vs 5 | 0.91 | 0.88 | |||||||||
rs1799983 G/T | eNOS Glu298Asp | Genotype | |||||||||
GG | 0.799 | 0.808 | 0.756 | 0.766 | 0.830 | 0.876 | 1 vs 2 | 0.59 | 0.30 | ||
GT | 0.184 | 0.178 | 0.211 | 0.216 | 0.169 | 0.123 | 1 vs 3 | 0.84 | 0.37 | ||
TT | 0.016 | 0.013 | 0.032 | 0.016 | 0.000 | 0.000 | 1 vs 4 | 0.68 | 0.63 | ||
Allele | 1 vs 5 | 0.41 | 0.21 | ||||||||
G | 0.892 | 0.897 | 0.862 | 0.775 | 0.915 | 0.938 | 2 vs 3 | 0.82 | 0.98 | ||
T | 0.108 | 0.103 | 0.138 | 0.125 | 0.085 | 0.062 | 4 vs 2 | 0.31 | 0.16 | ||
2 vs 5 | 0.09 | 0.02 | |||||||||
HWE p | 0.387 | 0.770 | 0.211 | 0.941 | 0.499 | 0.597 | 3 vs 4 | 0.51 | 0.21 | ||
3 vs 5 | 0.20 | 0.04 | |||||||||
4 vs 5 | 0.47 | 0.48 |