Fig. 4
From: Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope
Main molecular mechanisms involved in exercise-induced cardiac regeneration. AKT1: protein kinase B; ATF7: activating transcription factor 7; CEBP/β: CCAAT enhancer-binding protein beta; CITED4: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxyl-terminal domain 4; IGF1: insulin-like growth factor 1; IGF1R: insulin-like growth factor 1 receptor; HIPK1: homeodomain-interacting protein kinase 1; HMBOX1: homeobox containing 1; IRS1/2: insulin receptor substrate 1; PI3K: phosphatidylinositol 3-kinase; TIMP3: TIMP metallopeptidase inhibitor 3