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Fig. 3 | Sports Medicine - Open

Fig. 3

From: Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope

Fig. 3

Main molecular mechanisms involved in exercise-induced neural regeneration. AKT: protein kinase B; BDNF: brain-derived neurotrophic factor; JAK2: Janus kinase 2; GH: growth hormone; GHR: growth hormone receptor; IGF1: insulin-like growth factor 1; IGF1R: insulin-like growth factor 1 receptor; NICD: notch intracellular domain; Notch1: notch receptor 1; TRKB: neurotrophic tyrosine kinase, receptor, type 2; PF4: platelet factor 4; RIT1: Ras-like without CAAX 1; ROS: reactive oxygen species; SOX2: SRY-box transcription factor 2; STAT3: signal transducer and activator of transcription 3

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