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Table 3 Left ventricle ventricular strain and twisting mechanics

From: Does Hypoxia and Stress Erythropoiesis Compromise Cardiac Function in Healthy Adults? A Randomized Trial

 

Pre

Post

Altitude training effect

Time × treatment effect

Placebo (n)

rHuEPO (n)

Placebo (n)

rHEPO (n)

GCS (%)

24.3 ± 2.91 (19)

25.1 ± 3.43 (12)

27.9 ± 4.16 (19)

26.8 ± 2.80 (12)

0.005

0.280

GLS (%)

18.9 ± 2.15 (19)

18.3 ± 2.13 (12)

18.8 ± 1.94 (19)

19.0 ± 1.99 (12)

0.545

0.441

Twist peak (º)

5.03 ± 2.14 (18)

4.78 ± 3.14 (11)

6.32 ± 2.31 (18)

6.67 ± 1.91 (11)

0.020

0.934

Peak twisting velocity (º/seg)

50.4 ± 23.84 (18)

51.2 ± 24.75 (11)

51.4 ± 21.67 (18)

46.0 ± 11.38 (11)

0.725

0.599

% Untwist under IVRT

55.0 ± 17.54 (17)

62.4 ± 22.89 (12)

65.4 ± 19.66 (17)

54.9 ± 22.89 (12)

0.792

0.107

Peak untwisting velocity (º/seg)

81.5 ± 32.35 (18)

97.7 ± 51.00 (12)

91.8 ± 33.82 (18)

67.3 ± 26.57 (12)*

0.296

0.038

Untwist velocity/peak twist

22.5 ± 20.57 (17)

24.7 ± 17.03 (12)

16.7 ± 13.83 (17)

12.6 ± 8.54 (12)

0.040

0.464

  1. Results are means ± SD (number of subjects) and 2 (group) × 2 (time) ANOVA p values.
  2. GCS global circumferential strain, GLS global longitudinal strain, IVRT interventricular relaxation time.
  3. *p < 0.05 vs Placebo Post