Skip to main content

Table 2 Interpretation of hepatitis B virus blood tests

From: Chronic Viral Hepatitis in Elite Athletes: Approaches to Risk Assessment, Prevention and Management

HBsAg

Anti-HBc

Anti-HBs

HBeAg

HBV DNA

Interpretation

 + 

 + 

 − 

 + or  − 

 + 

Recently acquired HBV

Chronic hepatitis B infection (if persists for ≥ 6 months)

 − 

 + 

 − 

 − 

 + 

Occult hepatitis B infection from chronic carriers who lose the HBsAg

Occult hepatitis B infection from chronic carriers with surface antigen mutation

‘Window period’ of recently acquired HBV

 − 

 + 

 − 

 − 

 − 

Resolved acute infection

 − 

 − 

 + 

 − 

 − 

Immunity from vaccination

 − 

 + 

 + 

 − 

 − 

Immunity from natural infection

 − 

 − 

 − 

 − 

 − 

No prior exposure to HBV

No protective antibody response following vaccination

 − 

 − 

 − 

 − 

 + 

‘Window period’ of recently acquired HBV

  1. Anti-HBc antibody to hepatitis B core antigen; anti-HBs antibody to hepatitis B surface antigen; DNA deoxy-ribonucleic acid; HBeAg hepatitis e antigen; HBV hepatitis B virus