| LAD-test diagnostic accuracy (per-protocol results) | LAD-test diagnostic accuracy (as-treated results) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Expert clinician | Advanced clinician | Novice clinician | Expert clinician | Advanced clinician | Novice clinician | ||||||
 | Test session-1 | Test session-1 | ||||||||||
 |  | 95% CI |  | 95% CI |  | 95% CI |  | 95% CI |  | 95% CI |  | 95% CI |
Sensitivity | 57% | 29%; 82% | 86% | 57%; 98% | 64% | 35%; 87% | 56% | 30%; 80% | 75% | 48%; 93% | 56% | 30%; 80% |
Specificity | 83% | 70%; 93% | 98% | 89%; 100% | 94% | 83%; 99% | 85% | 71%; 94% | 98% | 88%; 100% | 93% | 82%; 99% |
PPV | 50% | 25%; 75% | 92% | 64%; 100% | 75% | 43%; 95% | 56% | 30%; 80% | 92% | 64%; 100% | 75% | 43%; 95% |
NPV | 87% | 74%; 95% | 96% | 86%; 100% | 90% | 78%; 97% | 85% | 71%; 94% | 92% | 80%; 98% | 86% | 73%; 94% |
LR +  | 3.43 | 1.57; 7.47 | 41.14 | 5.85; 289.53 | 10.29 | 3.21; 32.91 | 3.70 | 1.65; 8.29 | 34.5 | 4.86; 244.70 | 8.63 | 2.66; 27.97 |
LR- | 0.51 | 0.28; 0.95 | 0.15 | 0.04; 0.53 | 0.38 | 0.19; 0.77 | 0.52 | 0.29; 0.91 | 0.26 | 0.11; 0.60 | 0.47 | 0.27; 0.82 |
 | Youden Index | Youden Index | ||||||||||
 | 40% | 84% | 58% | 41% | 73% | 49% | ||||||
 | Agreement with MRI findings | Agreement with MRI findings | ||||||||||
 | 77% | 95% | 87% | 77% | 92% | 84% | ||||||
 | Test Session-2 | Test Session-2 | ||||||||||
Sensitivity | 57% | 22%; 82% | 86% | 57%; 98% | 79% | 49%; 95% | 56% | 30%; 80% | 75% | 48%; 93% | 69% | 41%; 89% |
Specificity | 90% | 77%; 97% | 96% | 86%; 99% | 92% | 80%; 98% | 91% | 79%; 98% | 96% | 85%; 99% | 91% | 79%; 98% |
PPV | 62% | 32%; 86% | 86% | 57%; 98% | 73% | 45%; 92% | 69% | 39%; 91% | 86% | 57%; 98% | 73% | 45%; 92% |
NPV | 88% | 75%; 95% | 96% | 86%; 99% | 94% | 82%; 99% | 86% | 73%; 94% | 92% | 80%; 98% | 89% | 77%; 96% |
LR +  | 5.49 | 2.13; 14.12 | 20.57 | 5.21; 81.24 | 9.43 | 3.55; 25.06 | 6.47 | 2.31; 18.14 | 17.25 | 4.32; 68.89 | 7.91 | 2.93; 21.34 |
LR- | 0.48 | 0.26; 0.88 | 0.15 | 0.04; 0.54 | 0.23 | 0.09; 0.64 | 0.48 | 0.27; 0.84 | 0.26 | 0.11; 0.61 | 0.34 | 0.17; 0.71 |
 | Youden Index | Youden Index | ||||||||||
 | 47% | 82% | 71% | 47% | 71% | 60% | ||||||
 | Agreement with MRI findings | Agreement with MRI findings | ||||||||||
 | 82% | 94% | 89% | 82% | 90% | 85% |