Table 4 Association between serum bilirubin concentration and (TA)n UGT1A1 gene promoter variants
From: Serum Bilirubin Concentrations and the Prevalence of Gilbert Syndrome in Elite Athletes
UGT1A1 genotype | Elite athletes (n = 136) | General population (n = 605) | ||||||
|---|---|---|---|---|---|---|---|---|
Males (n = 90) | Females (n = 46) | Males (n = 279) | Females (n = 326) | |||||
n | Bilirubin | n | Bilirubin | n | Bilirubin | n | Bilirubin | |
(TA)6/6 | +35 (38.9%) | 9.8 (8.1–13) | 21 (45,7%) | 8.3* (6.3–9.9) | 121 (43.4%) | 9.2 (6.7–11.5) | ++145 (44.5%) | 6.5 (4.7–9.1) |
(TA)6/7 | 41 (45.6%) | 14.0* (10.5–17) | 17 (37%) | 10.4* (8.5–13) | 143 (51.3%) | 11.3 (8.0–15.2) | 151 (46.3%) | 8.2 (6.2–10.4) |
(TA)7/7 | 14 (15.6%) | 28.6 (18.5–33.5) | 8 (17.4%) | 22.2* (15.8–25.5) | 38 (13.6%) | 21.6 (14.6–28.4) | 30 (9.2%) | 14.6 (10.0–19.8) |
P-value** | < 0.05 | < 0.05 | ||||||