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Table 1 Studies investigating CBF responses to dynamic resistance exercise

From: The Acute Cardiorespiratory and Cerebrovascular Response to Resistance Exercise

  Intensity Exercise performed Cohort Contraction number and duty cycle CBF metrics VM CBF response MAP response
Dickerman et al. [62] 100% of 1RM Bilateral leg press Mean age: 31
n: 9
Healthy resistance trained males
Duty cycle: Not stated
Number: 1
Unilateral MCAv – averaged across exercise Yes Mean decrease in MCAvmean of 16 cm.s-1. Unclear if pre exercise hyperventilation contributed as neither PETCO2 or PaCO2 were reported Not reported
Edwards et al. [12] Self-selected 10RM, equates to ~75% of MVC Bilateral leg press Mean age: 21
n: 9
Healthy resistance trained participants (6 females)
Duty cycle: not stated
Number: 10
Unilateral MCAv – averaged across exercise No No change during exercise but acute reduction in MCAvmean (mean 7 cm.s-1) below rest within 5s of exercise cessation Mean increase of ~15 mm HG in MAP during exercise with no post exercise hypotension reported.
Koch et al. [63] Endurance: 50–60% of maximum
Strength: 80–90% of maximum
Bilateral leg extension Mean age: males = 25, females = 24
n: 39
Healthy resistance trained participants (17 females)
Duty cycle: ~2s contraction time
Number: Until exhaustion. Endurance maximum of 23 repetitions and strength maximum of 8 repetitions.
Bilateral MCAv No – but brief VM could not be excluded. 15–30% increases in MCAvmean in both intensities examined. Temporarily impaired autoregulation following exercise with evidence of presyncopal reactions. Increase at both intensities and rapid decline following exercise.
Moralez et al. [64] Estimated 10RM Bilateral leg press exercise Mean age: 24
n: 10
Healthy males
Duty cycle: 10 repetitions per 30s (0.33hz)
Number: 10 Repetitions
Unilateral MCAv – averaged across exercise No Increase in MCAvmean.
Acute reduction when standing immediately following exercise
Increase in MAP. Acute reduction upon standing immediately following exercise
Perry et al. [55] 30, 60 and 90% of 6RM Upright squatting Mean age: 26
n: 12
Healthy resistance trained males
Duty cycle: 2s eccentric and 2s concentric
Number: 2 and 6 repetitions
Unilateral MCAv. Peak MCAv (at onset of concentric phase) analysed per repetition and absolute decrease following exercise Yes, only observed at 90% 6RM Similar mean increases of 31% in peak MCAvmean across all intensities. Larger decrease in MCAvmean post exercise at 90% 6RM. Intensity dependent increase in MAP during exercise and reduction immediately following exercise.
Romero and Cooke [65] 80% of 6RM Bilateral leg press Mean age: 26
n: 10
Healthy resistance trained participants (5 females)
Duty cycle: Not stated
Number: 10 Repetitions
Unilateral MCAv – averaged across exercise No 12% increase in MCAvmean without pre-exercise hyperventilation. Acute reduction when standing immediately following exercise. Pre exercise hyperventilation reduced MCAv during exercise. Increase in MAP. Acute reduction upon standing immediately following exercise
  1. MVC maximal voluntary contraction, MCAv middle cerebral artery blood velocity, PCAv posterior cerebral artery blood velocity, PETCO2 partial pressure of end-tidal carbon dioxide, PaCO2 partial pressure of arterial carbon dioxide, MAP mean arterial blood pressure, RM repetition maximum, VA vertebral artery, CBF cerebral blood flow, VM Valsalva manoeuvre