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Table 3 Effect of ADT on body composition, metabolism and physical function in the UC group at 12 months

From: Androgen deprivation in prostate cancer: benefits of home-based resistance training

  Baseline (n = 10) 12 months (n = 10) p value
Total mass (kg) 80.1 (3.0) 82.0 (3.0) 0.002
BCM (%) 43.6 (2.0) 39.0 (1.4) < 0.001
FM (%) 29.4 (2.1) 34.9 (1.5) < 0.001
Neck of femur BMD (left total) 1.011 (0.04) 1.001 (0.04) 0.28
Neck of femur BMD (right total) 1.01 (0.05) 0.99 (0.04) 0.13
Lumbar spine BMD 1.42 (0.06) 1.36 (0.07) 0.005
Fasting glucose (mmol/L) 4.7 (0.2) 5.4 (0.2) < 0.001
Fasting insulin (IU/L) 7.1 (2.2) 11.7 (2.3) 0.22
Matsuda index 6.5 (1.0) 4.7 (0.8) 0.002
HOMA-IR 1.6 (0.5) 2.9 (0.7) 0.11
Hepatic insulin resistance 43.7 (12.5) 74.0 (22.7) 0.008
Muscle insulin resistance 1.0 (0.4) 1.3 (0.6) 0.38
Co-ordinated stability (corners) 0.5 (0.5) 0.8 (0.3) 0.05
Right hand grip (N) 37.5 (1.8) 33.2 (1.7) < 0.001
Left hand grip (N) 34.0 (1.5) 30.9 (1.6) 0.004
Upper limb strength (N) 150.8 (14.1) 145.8 (11.3) 0.35
Lower limb strength (N) 297.2 (26.7) 239.5 (15.6) 0.02
Sit-to-stand test (number) 17.0 (1.3) 18 (1.5) 0.17
TUGT (s) 5.8 (0.3) 6.0 (0.3) 0.04
SF36v2 MCS score 58.4 (1.3) 55.4 (2.1) 0.08
  1. Data are presented as mean ± S.E.M; p value represents change compared to baseline in the UC group at 12 months; BCM body cell mass, FM fat mass, BMD bone mineral density, TUGT timed get-up-and-go test, IGF-1 insulin-like growth factor, IGFBP-3 insulin-like growth factor binding protein 3
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