Skip to main content

Table 3 Effect of ADT on body composition, metabolism and physical function in the UC group at 12 months

From: Androgen deprivation in prostate cancer: benefits of home-based resistance training

 

Baseline (n = 10)

12 months (n = 10)

p value

Total mass (kg)

80.1 (3.0)

82.0 (3.0)

0.002

BCM (%)

43.6 (2.0)

39.0 (1.4)

< 0.001

FM (%)

29.4 (2.1)

34.9 (1.5)

< 0.001

Neck of femur BMD (left total)

1.011 (0.04)

1.001 (0.04)

0.28

Neck of femur BMD (right total)

1.01 (0.05)

0.99 (0.04)

0.13

Lumbar spine BMD

1.42 (0.06)

1.36 (0.07)

0.005

Fasting glucose (mmol/L)

4.7 (0.2)

5.4 (0.2)

< 0.001

Fasting insulin (IU/L)

7.1 (2.2)

11.7 (2.3)

0.22

Matsuda index

6.5 (1.0)

4.7 (0.8)

0.002

HOMA-IR

1.6 (0.5)

2.9 (0.7)

0.11

Hepatic insulin resistance

43.7 (12.5)

74.0 (22.7)

0.008

Muscle insulin resistance

1.0 (0.4)

1.3 (0.6)

0.38

Co-ordinated stability (corners)

0.5 (0.5)

0.8 (0.3)

0.05

Right hand grip (N)

37.5 (1.8)

33.2 (1.7)

< 0.001

Left hand grip (N)

34.0 (1.5)

30.9 (1.6)

0.004

Upper limb strength (N)

150.8 (14.1)

145.8 (11.3)

0.35

Lower limb strength (N)

297.2 (26.7)

239.5 (15.6)

0.02

Sit-to-stand test (number)

17.0 (1.3)

18 (1.5)

0.17

TUGT (s)

5.8 (0.3)

6.0 (0.3)

0.04

SF36v2 MCS score

58.4 (1.3)

55.4 (2.1)

0.08

  1. Data are presented as mean ± S.E.M; p value represents change compared to baseline in the UC group at 12 months; BCM body cell mass, FM fat mass, BMD bone mineral density, TUGT timed get-up-and-go test, IGF-1 insulin-like growth factor, IGFBP-3 insulin-like growth factor binding protein 3