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Table 4 Median (p95 confidence interval) ACTH/cortisol ratios during insulin tolerance test (ITT)

From: Hypothalamic-Pituitary-Adrenal (HPA) Axis Functioning in Overtraining Syndrome: Findings from Endocrine and Metabolic Responses on Overtraining Syndrome (EROS)—EROS-HPA Axis

ACTH/cortisol ratio

OTS athletes (OTS) (n = 14)

Healthy athletes (ATL) (n = 25)

Non-active subjects (NCS) (n = 12)

p

Basal

184.9 (90.8–332.5)

141.5 (77.4–270.1)

178.0 (91.9–347.3)

n/s

During hypoglycemia

252.3 (77.1–1312.1)

363.5 (111.3–1421.3)

332.9 (122.0–1976.3)

n/s

30′ after hypoglycemia

156.0* (60.4–598.0)

286.2& (96.6–986.5)

321.9 (146.3–723.6)

0.03

  1. Differences between OTS and ATL: *p < 0.05
  2. Differences between ATL and NCS: & p < 0.05
  3. CI confidence interval