Gene | Symbol | Polymorphism | Genotype (2 “optimal” endurance genotype) | Frequency (%) | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Gorkha (TB) | Gorkha (IA) | HAN (TB) | Indian lowlander (IA) | Gujrati Houston (GIH, IA) | Han Chinese Beijing (CHB, ST) | JPT | Caucasian (CEU) | ||||
Angiotensin converting enzyme (Peptidyl dipeptidase A) | ACE | 287 bp I/D (rs1799752) | 0 = DD, 1 = ID, 2 = II | 10, 47, 43 | 12, 42, 46a | 04, 55, 41a | 24, 51, 25a | – | 12, 45, 43d | 12,47,41f | 30,51,19g |
Alpha actinin 3 | ACTN3 | Arg(R)577Ter(X) (rs1815739) | 0 = RR, 1 = RX, 2 = XX | 37, 48, 15 | 25, 52, 23a | 19, 65, 16 | 18, 56, 26a | 14, 59, 27c | 43, 39, 17c | 21, 61, 17c | 20, 58, 22 c |
Creatine kinase, muscle | CKMM | A/G NcoI (rs8111989) | 0 = GG, 1 = AG, 2 = AA | 05, 30, 65 | 08, 45, 47 | 05, 35, 60 | 16, 39, 46 | 22, 39, 38c | 04, 34, 61c | 05, 27, 68c | 05, 43, 51 c |
Endothelial nitric oxide synthase | eNOS | Glu 298Asp (rs1799983) | 0 = TT, 1 = GT, 2 = GG | 02, 18, 80 | 06, 29, 65 | 02, 26, 72b | 02, 33, 65 | – | 0, 22, 78e | 14, 86, 0c | 08, 51, 40 c |