Effect of Repeated Whole Blood Donations on Aerobic Capacity and Hemoglobin Mass in Moderately Trained Male Subjects: A Randomized Controlled Trial

Meurrens, Julie; Steiner, Thomas; Ponette, Jonathan; Janssen, Hans Antonius; Ramaekers, Monique; Wehrlin, Jon Peter; Vandekerckhove, Philippe; Deldicque, Louise

doi:10.1186/s40798-016-0067-7

Sports Medicine - Open

Table 4 Effect of repeated blood donations on hematological parameters

From: Effect of Repeated Whole Blood Donations on Aerobic Capacity and Hemoglobin Mass in Moderately Trained Male Subjects: A Randomized Controlled Trial

		Test series 1					Test series 2					Test series 3
		-1w	2d	1w	2w	4w	-1w	2d	1w	2w	4w	-1w	2d	1w	2w	4w
Hematocrit	P	46.6 ± 1.2	46.4 ± 0.6	46.1 ± 1.0	46.4 ± 1.3	46.1 ± 1.1	44.5 ± 1.5	45.3 ± 1.5	44.7 ± 1.4	46.2 ± 1.5	46.3 ± 1.5	43.5 ± 1.6	45.9 ± 1.2	46.0 ± 1.2	45.9 ± 0.9	45.3 ± 1.5
(%)	D	45.8 ± 0.6	40.9 ± 0.9***	41.9 ± 0.6***	42.4 ± 0.5***	43.9 ± 0.5**	44.5 ± 0.5###	42.2 ± 0.6***	41.0 ± 0.5***	43.0 ± 0.4**	43.2 ± 0.5**	43.8 ± 0.5###	41.7 ± 0.7***	41.9 ± 0.6***	42.1 ± 0.7***	43.4 ± 0.5
Hemoglobin	P	15.9 ± 0.6	15.7 ± 0.3	15.5 ± 0.5	15.4 ± 0.6	15.3 ± 0.5	15.0 ± 0.7	15.0 ± 0.7	14.9 ± 0.7	15.4 ± 0.7	15.3 ± 0.7	14.7 ± 0.8	15.2 ± 0.6	15.2 ± 0.6	15.2 ± 0.5	15.3 ± 0.8
(g/dl)	D	15.6 ± 0.2	13.7 ± 0.3***	14.2 ± 0.2***	14.2 ± 0.2***	14.5 ± 0.2***	14.9 ± 0.2###	14.0 ± 0.3***	13.7 ± 0.2***	14.2 ± 0.2***	14.4 ± 0.2**	14.6 ± 0.2###	13.7 ± 0.3***	14.1 ± 0.2**	14.1 ± 0.3**	14.5 ± 0.2
Iron	P	112 ± 20	101 ± 18	83 ± 17	98 ± 30	99 ± 20	85 ± 8	99 ± 35	78 ± 23	82 ± 11	110 ± 27	84 ± 19	136 ± 31	85 ± 13	133 ± 15	127 ± 36
(μg/dl)	D	106 ± 9	90 ± 8	74 ± 8**	66 ± 7***	96 ± 6	115 ± 20	101 ± 13	66 ± 7**	81 ± 10*	69 ± 6**	97 ± 9#	109 ± 9	76 ± 10	82 ± 11	99 ± 12
Ferritin	P	72 ± 12	64 ± 14	56 ± 11	53 ± 11	58 ± 11	64 ± 16	50 ± 11	68 ± 18	64 ± 16	59 ± 11	77 ± 22	71 ± 17	82 ± 15	76 ± 15	69 ± 13
(μg/l)	D	55 ± 8	45 ± 7*	43 ± 8*	37 ± 8***	27 ± 5***	40 ± 6##	42 ± 7	27 ± 4**	28 ± 3*	23 ± 4**	41 ± 5###	37 ± 5	30 ± 5***	29 ± 4***	33 ± 5**
MCH	P	29.9 ± 0.6	29.7 ± 0.6	29.4 ± 0.6***	29.4 ± 0.7**	29.4 ± 0.6**	29.9 ± 0.5###	29.4 ± 0.5	29.8 ± 0.5	29.9 ± 0.5	29.5 ± 0.6	29.8 ± 0.7##	29.6 ± 0.6	29.5 ± 0.5	29.6 ± 0.5	30.0 ± 0.6
(pg)	D	30.0 ± 0.3	29.6 ± 0.4**	29.7 ± 0.4**	29.4 ± 0.3***	29.5 ± 0.4***	29.4 ± 0.4###	29.3 ± 0.4	29.4 ± 0.4	29.3 ± 0.4	29.1 ± 0.4	29.0 ± 0.4##	28.6 ± 0.4**	29.3 ± 0.4*	29.0 ± 0.5	29.1 ± 0.4
MCHC	P	34.1 ± 0.4	33.7 ± 0.4*	33.6 ± 0.5***	33.2 ± 0.5**	33.1 ± 0.4**	33.6 ± 0.5##	33.1 ± 0.6*	33.3 ± 0.6	33.3 ± 0.5	33.0 ± 0.6*	33.8 ± 0.8###	33.1 ± 0.7	33.0 ± 0.6	33.2 ± 0.6	33.6 ± 0.7
(g/dl)	D	34.0 ± 0.2	33.6 ± 0.2**	33.8 ± 0.2*	33.4 ± 0.2***	33.1 ± 0.3***	33.6 ± 0.3###	33.2 ± 0.3	33.4 ± 0.2	33.1 ± 0.2*	33.3 ± 0.3	33.4 ± 0.3##	32.7 ± 0.3***	33.6 ± 0.2	33.3 ± 0.3	33.4 ± 0.3
RDW	P	12.9 ± 0.2	12.9 ± 0.2	13.0 ± 0.2	13.2 ± 0.2	13.2 ± 0.2*	13.1 ± 0.3#	13.2 ± 0.4	13.1 ± 0.4	13.2 ± 0.4	13.1 ± 0.3	13.2 ± 0.5##	13.4 ± 0.5	13.4 ± 0.5	13.4 ± 0.5	13.4 ± 0.6
(%)	D	12.8 ± 0.1	12.7 ± 0.1	12.8 ± 0.1	12.9 ± 0.1	13.0 ± 0.1*	12.6 ± 0.1	12.7 ± 0.1**	13.0 ± 0.1***	12.9 ± 0.1	12.8 ± 0.1	13.2 ± 0.1###	13.4 ± 0.2	13.3 ± 0.1	13.4 ± 0.1	13.1 ± 0.1
RBC	P	5.3 ± 0.2	5.3 ± 0.1	5.3 ± 0.2	5.3 ± 0.2	5.2 ± 0.2	5.0 ± 0.2	5.1 ± 0.2	5.0 ± 0.2	5.1 ± 0.2	5.2 ± 0.1	5.0 ± 0.2	5.2 ± 0.1	5.2 ± 0.1	5.1 ± 0.1	5.1 ± 0.2
(10¹²/l)	D	5.2 ± 0.1	4.6 ± 0.1***	4.8 ± 0.1***	4.8 ± 0.1***	4.9 ± 0.1**	5.1 ± 0.1###	4.8 ± 0.1***	4.7 ± 0.1***	4.9 ± 0.1**	4.9 ± 0.1*	5.1 ± 0.1###	4.8 ± 0.1***	4.8 ± 0.1***	4.8 ± 0.1***	5.0 ± 0.1

Values are means ± SEM (n = 7 in P and n = 13 in D for test series 1; n = 5 in P and n = 13 in D for test series 2 and 3. MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, RDW red blood cell distribution width, RBC red blood cell count, P placebo, D donation. ^# p < 0.05, ^## p < 0.01, ^### p < 0.001 vs. -1w of test series 1, same group. *p < 0.05, **p < 0.01, ***p < 0.001 vs. -1w of the same test series, same group

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