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Table 3 Measures of autonomic cardiovascular regulation before and after HIRREM

From: A Preliminary Study of the Effectiveness of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology in the Treatment of Athletes with Persisting Post-concussion Symptoms

Measure

Before HIRREM mean ± SE

After HIRREM mean ± SE

Paired t test p values

Wilcoxon p values

BRS Sequence Up (ms/mmHg)

23.5 ± 3.3

32.3 ± 5.2

0.019

0.041

BRS Sequence Down (ms/mmHg)

19.9 ± 2.4

34.0 ± 6.0

0.005

0.004

BRS Sequence All (ms/mmHg)

21.9 ± 2.6

43.1 ± 10.6

0.034

0.002

HF alpha (ms/mmHg)

25.3 ± 2.6

37.4 ± 5.6

0.027

0.073

SDNN (ms)

57.1 ± 4.0

71.2 ± 7.1

0.023

0.005

RMSSD (ms)

54.9 ± 6.0

61.6 ± 7.7

>0.2

>0.2

LF (ms2)

1397 ± 223

1840 ± 368

0.131

0.188

HF (ms2)

1715 ± 465

2155 ± 564

>0.2

>0.2