Fig 1

Individual changes in mediators of inflammation in recreational athletes after running either a marathon or half-marathon race. *p < 0.05, **p < 0.01, and ***p < 0.001 for comparisons between pre- and post-race values of all runners at given time points. ^§ p < 0.05 and ^§§ p < 0.01 for comparisons of changes in values between full- and half-marathon runners. The highest levels of suPAR, CRP, IL-6, TNF-α, and IL-10 were noted from a marathon runner who also suffered from the most severe symptoms of post-race fatigue (case indicated by arrows). CD163 macrophage receptor for haptoglobin-hemoglobin complexes, CRP C-reactive protein, IL interleukin, suPAR soluble urokinase-type plasminogen activator receptor, TGF-β transforming growth factor-β, TNF-α tumor necrosis factor-α, WBC white blood cells (leukocytes)